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Milestone as Danish corona vaccine works on mice

Ayee Macaraig
June 10th, 2020


This article is more than 4 years old.

Clinical trials on humans are planned before the end of the year

Rejected asylum seekers could face forced testing (photo: Pixabay)

Researchers from the University of Copenhagen have reached a milestone in their work to develop a vaccine against the coronavirus. Their vaccine has worked on mice and clinical trials on humans are planned before the end of the year.

The university said researchers spent the past two months testing the vaccine on mice, and that this has produced large amounts of antibodies able to neutralise the coronavirus. This is significant because it paves the way for studying the vaccine’s effectiveness on humans.

“It is very promising. We hope to be able to launch the first clinical trials on humans in six months,” said Adam Sander, an associate professor who is part of a group of 10 to 15 researchers working on the vaccine.

Stronger capacity
The researchers said the capacity of the blood of the mice to fight the virus was significantly greater than that seen in COVID-19 vaccines by other researchers and companies.

Various scientists and companies worldwide are racing to develop a vaccine, including in the US, UK and China.

The Danish researchers’ vaccine uses technology called cVLP or capsid Virus-Like Particle. The team hopes that as with mice, the vaccine will enable humans to produce antibodies and become immune to the disease.

Humans different?
Some researchers were confident that the vaccine will also work on humans but others said it was still too early to tell.

“I have followed the scientific literature long enough to know that there are many things that have been seen to be good for mice but not so for people,” Søren Riis Paludan, a professor at Aarhus University’s Department of Biomedicine, told TV2.

The researchers are part of a consortium that received grants from the EU, the Gudbjørg and Ejnar Honoré Foundation, and the Carlsberg Foundation to develop a coronavirus vaccine.


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A survey carried out by Megafon for TV2 has found that 71 percent of parents have handed over children to daycare in spite of them being sick.

Moreover, 21 percent of those surveyed admitted to medicating their kids with paracetamol, such as Panodil, before sending them to school.

The FOLA parents’ organisation is shocked by the findings.

“I think it is absolutely crazy. It simply cannot be that a child goes to school sick and plays with lots of other children. Then we are faced with the fact that they will infect the whole institution,” said FOLA chair Signe Nielsen.

Pill pushers
At the Børnehuset daycare institution in Silkeborg a meeting was called where parents were implored not to bring their sick children to school.

At Børnehuset there are fears that parents prefer to pack their kids off with a pill without informing teachers.

“We occasionally have children who that they have had a pill for breakfast,” said headteacher Susanne Bødker. “You might think that it is a Panodil more than a vitamin pill, if it is a child who has just been sick, for example.”

Parents sick and tired
Parents, when confronted, often cite pressure at work as a reason for not being able to stay at home with their children.

Many declare that they simply cannot take another day off, as they are afraid of being fired.

Allan Randrup Thomsen, a professor of virology at KU, has heavily criticised the parents’ actions, describing the current situation as a “vicious circle”.

“It promotes the spread of viruses, and it adds momentum to a cycle where parents are pressured by high levels of sick-leave. If they then choose to send the children to daycare while they are still recovering, they keep the epidemic going in daycares, and this in turn puts a greater burden on the parents.”