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Evolving with the mutations: Forthcoming Danish COVID-19 vaccine has the variants in its sights

Ben Hamilton
March 8th, 2021


This article is more than 3 years old.

Pharma company Bavarian Nordic confirms via stock exchange today that it is ready to test on humans

Quite a few have caught it twice (photo: Pixabay)

Danish pharmaceutical company Bavarian Nordic is ready to test its COVID-19 vaccine on humans – and the indications are good that it will effectively be able to deal with the current mutations doing the rounds.

It has today informed the Copenhagen Stock Exchange that it is encouraged by data to the extent it can take its ABNCoV2 vaccine onto the next step. 

“We are pleased to report strong preclinical results for ABNCoV2, which support further development,” wrote Bavarian Nordic chief executive Paul Chaplin in the announcement.

The next generation
The ABNCoV2 vaccine has proved to be not only effective against COVID-19, but also against subsequent problems associated with the disease.

“While several vaccines have already been approved and widely used to combat the pandemic, the length and breadth of the protection they provide against new variants of the disease is unknown,” noted Chaplin.

“And it underlines the need to continue prioritising the development of the next generation of COVID-19 vaccines. COVID-19 is likely to continue with us as a contagious disease that needs to be managed.”

Combined Phase 1 and 2 study
The tests, a combined Phase 1 and 2 study, will be carried out on 42 healthy adults at the Radhoud Medical Center in the Netherlands.

If successful, a Phase 3 study will ensue, following which it will seek approval from the authorities.

The Bavarian Nordic vaccine is the result of the efforts of a consortium of companies and universities called PREVENT-nCoV, which has received financial support from the EU research fund Horizon 2020.


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A survey carried out by Megafon for TV2 has found that 71 percent of parents have handed over children to daycare in spite of them being sick.

Moreover, 21 percent of those surveyed admitted to medicating their kids with paracetamol, such as Panodil, before sending them to school.

The FOLA parents’ organisation is shocked by the findings.

“I think it is absolutely crazy. It simply cannot be that a child goes to school sick and plays with lots of other children. Then we are faced with the fact that they will infect the whole institution,” said FOLA chair Signe Nielsen.

Pill pushers
At the Børnehuset daycare institution in Silkeborg a meeting was called where parents were implored not to bring their sick children to school.

At Børnehuset there are fears that parents prefer to pack their kids off with a pill without informing teachers.

“We occasionally have children who that they have had a pill for breakfast,” said headteacher Susanne Bødker. “You might think that it is a Panodil more than a vitamin pill, if it is a child who has just been sick, for example.”

Parents sick and tired
Parents, when confronted, often cite pressure at work as a reason for not being able to stay at home with their children.

Many declare that they simply cannot take another day off, as they are afraid of being fired.

Allan Randrup Thomsen, a professor of virology at KU, has heavily criticised the parents’ actions, describing the current situation as a “vicious circle”.

“It promotes the spread of viruses, and it adds momentum to a cycle where parents are pressured by high levels of sick-leave. If they then choose to send the children to daycare while they are still recovering, they keep the epidemic going in daycares, and this in turn puts a greater burden on the parents.”