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Danish research closing in on vaccine for bone marrow cancer

Christian Wenande
October 30th, 2017


This article is more than 7 years old.

Vaccine mobilises the immune system to target and annihilate the cancer cells

Could immunotherapy be the way forward? (photo: Pixabay)

Danish researchers are inching closer to being able to launch the first vaccine trial that could ultimately lead to a cure for bone marrow cancer.

Morten Orebo Holmström, a doctor and PhD student at Zealand University Hospital in Roskilde, says his research, which is based on immunotherapy – treatment that uses the body’s own immune system to fight the cancer – has been more than promising thus far.

“We will commence with the first vaccinations on patients in the first half of 2018. The first trials will look into whether the vaccine is harmful or has serious side-effects,” Holmström told SN.dk.

READ MORE: Danish researchers on verge of cancer treatment breakthrough

Superseding transplantations
Holmström said he expects to become the first researcher in the world to develop this kind of immunotherapy vaccine.

“It works in the lab petri dishes, though we don’t yet know whether it will also work in the organism, but we believe it will.”

In nearly all instances of bone marrow cancer two genetic mutations are particularly seen, and the research has now proven that the immune system is capable of recognising and eradicating cancer cells that carry the two mutations (JAK2 or CALR).

Bone marrow cancer affects some 350 Danes every year and, as of now, the only cure is to have a bone marrow transplantation.


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A survey carried out by Megafon for TV2 has found that 71 percent of parents have handed over children to daycare in spite of them being sick.

Moreover, 21 percent of those surveyed admitted to medicating their kids with paracetamol, such as Panodil, before sending them to school.

The FOLA parents’ organisation is shocked by the findings.

“I think it is absolutely crazy. It simply cannot be that a child goes to school sick and plays with lots of other children. Then we are faced with the fact that they will infect the whole institution,” said FOLA chair Signe Nielsen.

Pill pushers
At the Børnehuset daycare institution in Silkeborg a meeting was called where parents were implored not to bring their sick children to school.

At Børnehuset there are fears that parents prefer to pack their kids off with a pill without informing teachers.

“We occasionally have children who that they have had a pill for breakfast,” said headteacher Susanne Bødker. “You might think that it is a Panodil more than a vitamin pill, if it is a child who has just been sick, for example.”

Parents sick and tired
Parents, when confronted, often cite pressure at work as a reason for not being able to stay at home with their children.

Many declare that they simply cannot take another day off, as they are afraid of being fired.

Allan Randrup Thomsen, a professor of virology at KU, has heavily criticised the parents’ actions, describing the current situation as a “vicious circle”.

“It promotes the spread of viruses, and it adds momentum to a cycle where parents are pressured by high levels of sick-leave. If they then choose to send the children to daycare while they are still recovering, they keep the epidemic going in daycares, and this in turn puts a greater burden on the parents.”