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Research project maps shared Danish genome

Stephen Gadd
August 10th, 2017


This article is more than 7 years old.

New Danish research will enhance our understanding of hereditary diseases

New genetic research could result in new and improved medicines being developed (image: Wikimedia/Webridge)

Researchers from three different universities – two in Denmark, one in China – have analysed the genomes of 50 families.

The fruits of their research has resulted in a new body of knowledge called the Danish Reference Genome.

READ ALSO: Scientists break genetic code for diabetes in Greenland

Professor Anders Børglum of the department of biomedicine and the centre for iSequencing at Aarhus University says the new reference genome can be used to enhance personalised medicine – for example, for mental disorders.

Providing a greater understanding
In future, he will be able to consult the genome and see whether the genetic variation that he suspects of contributing to a mental disorder is normal amongst healthy Danes or whether it is deviating from the norm.

“Discovering genetic variants that increase the risk of mental illness can also help give us a greater understanding of the biological mechanisms behind the disease, as the genes can put us on the right track,” explained Anders Børglum.

A long road
The work on sequencing the gene has taken five years.

Professor Søren Brunak from the Technical University of Denmark (DTU), one of the other universities involved in the project, says that further research is needed to establish causative relations between many of the new genotypes discovered and a disease.

“However, due to our strong research tradition, comprehensive health registers and existing biobanks, we are uniquely positioned to couple genomics and other types of health data on a large scale.”


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A survey carried out by Megafon for TV2 has found that 71 percent of parents have handed over children to daycare in spite of them being sick.

Moreover, 21 percent of those surveyed admitted to medicating their kids with paracetamol, such as Panodil, before sending them to school.

The FOLA parents’ organisation is shocked by the findings.

“I think it is absolutely crazy. It simply cannot be that a child goes to school sick and plays with lots of other children. Then we are faced with the fact that they will infect the whole institution,” said FOLA chair Signe Nielsen.

Pill pushers
At the Børnehuset daycare institution in Silkeborg a meeting was called where parents were implored not to bring their sick children to school.

At Børnehuset there are fears that parents prefer to pack their kids off with a pill without informing teachers.

“We occasionally have children who that they have had a pill for breakfast,” said headteacher Susanne Bødker. “You might think that it is a Panodil more than a vitamin pill, if it is a child who has just been sick, for example.”

Parents sick and tired
Parents, when confronted, often cite pressure at work as a reason for not being able to stay at home with their children.

Many declare that they simply cannot take another day off, as they are afraid of being fired.

Allan Randrup Thomsen, a professor of virology at KU, has heavily criticised the parents’ actions, describing the current situation as a “vicious circle”.

“It promotes the spread of viruses, and it adds momentum to a cycle where parents are pressured by high levels of sick-leave. If they then choose to send the children to daycare while they are still recovering, they keep the epidemic going in daycares, and this in turn puts a greater burden on the parents.”