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Danish discovery could revolutionise cancer treatment

Lucie Rychla
June 23rd, 2016


This article is more than 8 years old.

Researchers from the University of Copenhagen have found a way to kill cancer cells without harming healthy ones

A group of researchers from the University of Copenhagen (KU) has made a discovery that could prove significant in the battle against cancer.
The KU team, led by professor Anja Groth, identified a molecular mechanism that explains how a specific protein can repair DNA damage without harming healthy cells – knowledge that can be used in the development of new targeted cancer treatment.
Results of the team’s research have just been published in the noted science journal Nature.
Long way off
“We have shown how a cellular DNA repair protein is directed to lesions in DNA via modifications on histone proteins that are bound tightly to DNA. Cancer cells divide rapidly and experience a high load of DNA damage – without efficient repair systems these cells will die,” Groth told Medical Express.
Groth stressed that there was still a long way to go but believes the new discovery offered great potential.
According to the World Health Organisation, the global cost of cancer was estimated to be nearly 6,000 billion kroner in 2008, when about 7.6 million people died from the disease. Six years later, the number of cancer-related deaths has reached 8.2 million.

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A survey carried out by Megafon for TV2 has found that 71 percent of parents have handed over children to daycare in spite of them being sick.

Moreover, 21 percent of those surveyed admitted to medicating their kids with paracetamol, such as Panodil, before sending them to school.

The FOLA parents’ organisation is shocked by the findings.

“I think it is absolutely crazy. It simply cannot be that a child goes to school sick and plays with lots of other children. Then we are faced with the fact that they will infect the whole institution,” said FOLA chair Signe Nielsen.

Pill pushers
At the Børnehuset daycare institution in Silkeborg a meeting was called where parents were implored not to bring their sick children to school.

At Børnehuset there are fears that parents prefer to pack their kids off with a pill without informing teachers.

“We occasionally have children who that they have had a pill for breakfast,” said headteacher Susanne Bødker. “You might think that it is a Panodil more than a vitamin pill, if it is a child who has just been sick, for example.”

Parents sick and tired
Parents, when confronted, often cite pressure at work as a reason for not being able to stay at home with their children.

Many declare that they simply cannot take another day off, as they are afraid of being fired.

Allan Randrup Thomsen, a professor of virology at KU, has heavily criticised the parents’ actions, describing the current situation as a “vicious circle”.

“It promotes the spread of viruses, and it adds momentum to a cycle where parents are pressured by high levels of sick-leave. If they then choose to send the children to daycare while they are still recovering, they keep the epidemic going in daycares, and this in turn puts a greater burden on the parents.”